Bioinformatics for You is a comprehensive online course designed for beginners to unlock the power of bioinformatics in biological research. It is for those stepping into bioinformatics for the first time or looking to enhance their skills, this course provides the tools and insights to confidently analyze and interpret biological data.

INFORMATION SHEET

Aim:

To introduce participants to the journey into bioinformatics. The knowledge, skills, and mindset needed to leverage computational tools and techniques for biological research, data analysis, and innovation. It prepares undergraduates, graduates and researchers to contribute to the advancement of knowledge in the life sciences and make a positive impact on society.

Intended Audience:

Students/Lecturers/Researchers in Agriculture, Life Sciences, Science/Medical Life sciences, Science/Biology Education, Medical Doctors, Pathologists, and everyone irrespective of their discipline.

Course Logistics:

The course will run for approximately 23 days as it is going to be a video per day.

Course Curriculum:

The course curriculum will cover the following main themes:

𝗗𝗮𝘆 𝟭: 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝘁𝗼 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀

- This day provides an overview of bioinformatics, its role in biological research, and the tools and techniques used in the field.

𝗗𝗮𝘆 𝟮: 𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝘀 𝗶𝗻 𝗗𝗡𝗔 𝗦𝗲𝗾𝘂𝗲𝗻𝗰𝗶𝗻𝗴

- Covers the latest developments and technologies in DNA sequencing, including next-generation sequencing methods and their applications.

𝗗𝗮𝘆 𝟯: 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀 𝗳𝗼𝗿 𝗙𝗼𝗿𝗲𝗻𝘀𝗶𝗰 𝗦𝘁𝘂𝗱𝗶𝗲𝘀

- Focuses on how bioinformatics is used in forensic applications such as parental disputes and criminology, including DNA analysis and identification.

𝗗𝗮𝘆 𝟰: 𝗕𝗮𝘀𝗶𝗰𝘀 𝗼𝗳 𝗕𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗗𝗮𝘁𝗮𝗯𝗮𝘀𝗲𝘀

- Introduces biological databases, their importance, and how to navigate and retrieve data from them.

𝗗𝗮𝘆 𝟱: 𝗕𝗮𝘀𝗶𝗰𝘀 𝗼𝗳 𝗦𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝗔𝗹𝗶𝗴𝗻𝗺𝗲𝗻𝘁

- Explains the fundamental concepts of sequence alignment, a critical process in bioinformatics for comparing DNA, RNA, or protein sequences.

𝗗𝗮𝘆 𝟲: 𝗣𝗮𝗶𝗿𝘄𝗶𝘀𝗲 𝗮𝗻𝗱 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲 𝗦𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝗔𝗹𝗶𝗴𝗻𝗺𝗲𝗻𝘁

- Discusses the differences between pairwise and multiple sequence alignments and their applications in comparative genomics.

𝗗𝗮𝘆 𝟳: 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲 𝗦𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝗔𝗹𝗶𝗴𝗻𝗺𝗲𝗻𝘁 𝗧𝗼𝗼𝗹𝘀

- Covers software and resources for performing multiple sequence alignments, allowing you to compare multiple sequences simultaneously.

𝗗𝗮𝘆 𝟴: 𝗖𝗟𝗨𝗦𝗧𝗔𝗟𝗪 𝗦𝗼𝗳𝘁𝘄𝗮𝗿𝗲

- Focuses on the usage and features of the CLUSTALW software, a popular tool for multiple sequence alignment.

𝗗𝗮𝘆 9: 𝗕𝗶𝗼𝗘𝗱𝗶𝘁 𝗶𝗻 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀

- Focuses on BioEdit, a widely used software for sequence alignment, editing, and analysis.

𝗗𝗮𝘆 10: 𝗣𝗹𝗮𝗻𝘁 𝗚𝗲𝗻𝗼𝗺𝗶𝗰 𝗗𝗮𝘁𝗮 𝗮𝗻𝗱 𝗥𝗲𝘀𝗼𝘂𝗿𝗰𝗲𝘀 𝗮𝘁 𝗡𝗖𝗕𝗜

- Explores the genomic data and resources available for plant research at the National Center for Biotechnology Information (NCBI).

𝗗𝗮𝘆 𝟭1: 𝗡𝗖𝗕𝗜 𝗕𝗟𝗔𝗦𝗧

- Teaches the principles and protocols of the Basic Local Alignment Search Tool (BLAST) for sequence similarity searching.

𝗗𝗮𝘆 𝟭2: 𝗘𝘅𝗣𝗔𝗦𝘆 𝗣𝗼𝗿𝘁𝗮𝗹

- Introduces the ExPASy bioinformatics resource portal, which offers various tools and databases for protein research.

𝗗𝗮𝘆 𝟭3: 𝗣𝗿𝗶𝗺𝗲𝗿 𝗗𝗲𝘀𝗶𝗴𝗻𝗶𝗻𝗴 𝗧𝗼𝗼𝗹𝘀

- Covers tools and techniques for designing primers used in molecular biology experiments like PCR.

𝗗𝗮𝘆 𝟭4: 𝗣𝗿𝗶𝗺𝗲𝗿 𝗗𝗲𝘀𝗶𝗴𝗻𝗶𝗻𝗴 𝗳𝗼𝗿 𝗖𝗹𝗼𝗻𝗶𝗻𝗴

- Discusses primer design specific to cloning procedures and gene manipulation techniques.

𝗗𝗮𝘆 𝟭5: 𝗥𝗲𝘀𝘁𝗿𝗶𝗰𝘁𝗶𝗼𝗻 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗧𝗼𝗼𝗹𝘀

- Introduces tools for analyzing restriction enzyme sites and DNA cleavage patterns in molecular biology experiments.

𝗗𝗮𝘆 𝟭6: 𝗥𝗲𝘀𝘁𝗿𝗶𝗰𝘁𝗶𝗼𝗻 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗨𝘀𝗶𝗻𝗴 𝗡𝗘𝗕𝗰𝘂𝘁𝘁𝗲𝗿

- Focuses on using the NEBcutter tool for restriction enzyme analysis and DNA manipulation.

𝗗𝗮𝘆 𝟭7: 𝗞𝗘𝗚𝗚 𝗗𝗮𝘁𝗮𝗯𝗮𝘀𝗲

- Explores the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, a valuable resource for pathway and functional analysis.

𝗗𝗮𝘆 𝟭8: 𝗗𝗮𝘁𝗮𝗯𝗮𝘀𝗲 𝗳𝗼𝗿 𝗔𝗻𝗻𝗼𝘁𝗮𝘁𝗶𝗼𝗻, 𝗩𝗶𝘀𝘂𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻, 𝗮𝗻𝗱 𝗜𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗲𝗱 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 (𝗗𝗔𝗩𝗜𝗗)

- Introduces the DAVID platform for functional annotation and enrichment analysis of genes and proteins.

𝗗𝗮𝘆 𝟭9: 𝗚𝗲𝗻𝗼𝗺𝗲 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗕𝗿𝗼𝘄𝘀𝗲𝗿𝘀

- Covers the use of genome browsers for visualizing and analyzing genomic data, including popular platforms like UCSC Genome Browser.

𝗗𝗮𝘆 20: 𝗡𝗲𝘅𝘁-𝗚𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗼𝗻 𝗔𝗹𝗶𝗴𝗻𝗺𝗲𝗻𝘁 𝗧𝗼𝗼𝗹𝘀

- Discusses alignment tools and strategies for handling data from next-generation sequencing technologies.

𝗗𝗮𝘆 𝟮1: 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗠𝗮𝗿𝗸𝗲𝗿 𝗦𝘁𝗼𝗿𝗮𝗴𝗲 𝗗𝗮𝘁𝗮𝗯𝗮𝘀𝗲𝘀 𝗮𝗻𝗱 𝗗𝗮𝘁𝗮 𝗩𝗶𝘀𝘂𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻

- Explores databases and tools for storing molecular marker data, which is important in genetics and genomics research.

𝗗𝗮𝘆 𝟮2: 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝘁𝗼 𝗖𝗼𝗺𝗽𝘂𝘁𝗲𝗿-𝗔𝗶𝗱𝗲𝗱 𝗗𝗿𝘂𝗴 𝗗𝗲𝘀𝗶𝗴𝗻

- Introduces the concept of using computational methods in drug discovery and design.

𝗗𝗮𝘆 𝟮𝟯: 𝗙𝘂𝘁𝘂𝗿𝗲 𝗧𝗿𝗲𝗻𝗱𝘀 𝗶𝗻 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀

- Discusses upcoming trends and advancements in the field of bioinformatics, keeping participants informed about the latest developments.

Each day's topic will be replete with relevant case studies, practical examples, or interactive elements to enhance engagement and understanding.

Course completion:

Participants are eligible for a certificate that is optional (comes with a fee) after the course completion.

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